| Product Number |
ARP57940_P050 |
| Product Page |
www.avivasysbio.com/cebpb-antibody-n-terminal-region-arp57940-p050.html |
| Name |
CEBPB Antibody - N-terminal region (ARP57940_P050) |
| Protein Size (# AA) |
345 amino acids |
| Molecular Weight |
36kDa |
| NCBI Gene Id |
1051 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
CCAAT/enhancer binding protein (C/EBP), beta |
| Alias Symbols |
TCF5, IL6DBP, NF-IL6, C/EBP-beta |
| Peptide Sequence |
Synthetic peptide located within the following region: AIDFSPYLEPLGAPQAPAPATATDTFEAAPPAPAPAPASSGQHHDFLSDL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
He,D., (2008) Biochem. J. 412 (1), 153-162 |
| Description of Target |
CEBPB is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Protein Interactions |
CEBPA; UBC; EGR1; EP300; TP63; RB1; RELA; DAXX; CASP8; CASP1; SMARCA2; HDAC1; SMARCC1; SMARCB1; SMARCA4; SMARCA5; TAF9; ELAVL1; SUMO2; TRIM28; CEBPB; ATF3; CARM1; GSK3B; SUMO1; KAT2A; HDAC9; KAT2B; NCOR2; NCOR1; STAT3; PPARG; NRF1; CREBBP; ATF2; EHMT2; SP |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-CEBPB (ARP57940_P050) antibody |
| Blocking Peptide |
For anti-CEBPB (ARP57940_P050) antibody is Catalog # AAP57940 (Previous Catalog # AAPP32351) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human CEBPB |
| Uniprot ID |
P17676 |
| Protein Name |
CCAAT/enhancer-binding protein beta |
| Sample Type Confirmation |
CEBPB is supported by BioGPS gene expression data to be expressed in MCF7 |
| Protein Accession # |
NP_005185 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_005194 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
CEBPB |
| Predicted Species Reactivity |
Human, Rat, Cow, Dog, Pig, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 92%; Human: 100%; Pig: 100%; Rabbit: 100%; Rat: 85% |
| Image 1 | Human HepG2
 | WB Suggested Anti-CEBPB Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: HepG2 cell lysate |
|
| Image 2 | Human MCF7
 | Host: Rabbit
Target Name: CEBPB
Sample Type: Human MCF7
Antibody Dilution: 1.0ug/mlCEBPB is supported by BioGPS gene expression data to be expressed in MCF7 |
|
