| Sku |
AAP57940 |
| Old sku |
AAPP32351 |
| Price |
$99.00 |
| Name |
CEBPB Peptide - N-terminal region (AAP57940) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
CEBPB |
| Alias symbols |
C/EBP-beta, CRP2, IL6DBP, LAP, MGC32080, NF-IL6, TCF5 |
| Gene id |
1051 |
| Description of target |
CEBPB is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Swissprot id |
P17676 |
| Protein accession num |
NP_005185 |
| Nucleotide accession num |
NM_005194 |
| Protein size |
345 amino acids |
| Molecular weight |
36kDa |
| Application |
WB |
| Partner proteins |
DDIT3,EGR1,PRG2,SMAD4,ATF2,ATF4,CAMK2A,CCL3,CEBPA,CEBPB,CEBPD,CEBPG,CREB1,CREBBP,DDIT3,EGFR,EGR1,ELK1,EP300,ESR1,FOXO1,HMGA1,HMGB1,HNRNPK,HOMER3,HSF1,MAPK1,MAPK3,MED23,MYB,MYC,NFKB1,NOLC1,NR3C1,PTGES2,RB1,RELA,RPS6KA1,RPS6KA5,RUNX1,RUNX2,SMAD3,SMAD4,SMARCA4,SMARCB1,SMARCC1,SP1,SPI1,SPIB,SRF,STAT5A,STAT6,TAF9,TRIM28,AR,Atf2,CDK8,CEBPA,CEBPD,CEBPG,CREB1,DDIT3,EGFR,EGR1,EP300,ESR1,FOXO1,HMGA1,HNRNPK,HSF1,MAPK1,MED23,MED26,MYB,MYC,NFKB1,NOLC1,NR3C1,RARB,RB1,RELA,RUNX1,SMAD3,SMAD4,SMARCA2,SMARCC1,SP1,SPI1,SRF,TRIM28 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
He,D., (2008) Biochem. J. 412 (1), 153-162 |
| Description |
This is a synthetic peptide designed for use in combination with anti-CEBPB antibody (Catalog #: ARP57940_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
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| Tips |
See our General FAQ page. |
| Availability |
In Stock |
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