RAC1 Antibody - middle region (ARP57798_P050)

• Product Number: ARP57798_P050
• Name: RAC1 Antibody - middle region (ARP57798_P050)
• Protein Size (# AA): 192 amino acids
• Molecular Weight: 23 kDa
• NCBI Gene Id: 5879
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
• Alias Symbols: MIG5, MRD48, Rac-1, TC-25, p21-Rac1
• Peptide Sequence: Synthetic peptide located within the following region: LAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Description of Target: The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.
• Protein Interactions: PAK3; NCF2; KRT40; LZTS2; PAK6; C1QA; RHOB; XIAP; BIRC2; UBC; CDC23; USH1C; TRIO; srgp-1; EED; PRMT6; HACE1; NOXA1; ARFIP2; ITGA4; GRN; FN1; BRINP1; DIAPH3; BAIAP2; LTBP4; VWF; VCAM1; MTNR1A; COX3; LTBP3; CHN2; IGBP1; CLNS1A; PSAT1; Htt; PAK1; LRRK2; SH3R
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Enhanced Validation:

  WB	Y
  SPR
  YCHAROS

• Blocking Peptide: For anti-RAC1 (ARP57798_P050) antibody is Catalog # AAP57798 (Previous Catalog # AAPP44117)
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RAC1
• Uniprot ID: P63000-2
• Protein Name: Ras-related C3 botulinum toxin substrate 1
• Protein Accession #: NP_008839
• Purification: Affinity Purified
• Nucleotide Accession #: NM_006908
• Tested Species Reactivity: Human
• Gene Symbol: RAC1
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
• Application: WB, IHC
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%
• Image 1: Colon
  
  Rabbit Anti-RAC1 antibody
  Catalog Number: ARP57798
  Formalin Fixed Paraffin Embedded Tissue: Human Adult Colon
  Observed Staining: Cytoplasm in hepatocytes
  Primary Antibody Concentration: 1:600
  Secondary Antibody: Donkey anti-Rabbit-Cy3
  Secondary Antibody Concentration: 1:200
  Magnification: 20X
  Exposure Time: 0.5 – 2.0 sec
  
• Image 2: Human HepG2
  
  WB Suggested Anti-RAC1 Antibody Titration: 0.2-1 ug/ml
  Positive Control: HepG2 cell lysate