Product Number |
ARP41411_P050 |
Product Page |
www.avivasysbio.com/sftpb-antibody-middle-region-arp41411-p050.html |
Name |
SFTPB Antibody - middle region (ARP41411_P050) |
Protein Size (# AA) |
381 amino acids |
Molecular Weight |
42 kDa |
NCBI Gene Id |
6439 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Surfactant protein B |
Alias Symbols |
SP-B, PSP-B, SFTB3, SFTP3, SMDP1 |
Peptide Sequence |
Synthetic peptide located within the following region: PGALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGALAVAV |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Garmany,T.H., (2008) Pediatr. Res. 63 (6), 645-649 |
Description of Target |
SFTPB is the pulmonary-associated surfactant B protein (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a lipid-rich material that prevents lung collapse by lowering surface tension at the air-liquid interface in the alveoli of lung. SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Surfactant is composed of phospholipids and other surfactant-associated proteins. See also SFTPA1, SFTPC, and SFTPD. The SFTPB gene encodes the pulmonary-associated surfactant B protein (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a lipid-rich material that prevents lung collapse by lowering surface tension at the air-liquid interface in the alveoli of lung. SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Surfactant is composed of phospholipids and other surfactant-associated proteins (Clark et al., 1995 [PubMed 7644495]). See also SFTPA1 (MIM 178630), SFTPC (MIM 178620), and SFTPD (MIM 178635).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Protein Interactions |
CTSH; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Enhanced Validation |
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Datasheets/Manuals |
Printable datasheet for anti-SFTPB (ARP41411_P050) antibody |
Blocking Peptide |
For anti-SFTPB (ARP41411_P050) antibody is Catalog # AAP41411 (Previous Catalog # AAPP24149) |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human SFTPB |
Uniprot ID |
P07988 |
Protein Name |
Pulmonary surfactant-associated protein B |
Protein Accession # |
NP_000533 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_000542 |
Tested Species Reactivity |
Human, Mouse, Rat |
Gene Symbol |
SFTPB |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Sheep |
Application |
WB, IHC |
Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 92%; Rabbit: 85%; Rat: 100%; Sheep: 79% |
Image 1 | Human 721_B
| WB Suggested Anti-SFTPB Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: 721_B cell lysate |
|
Image 2 | Human MCF7 Whole Cell
| Host: Rabbit Target Name: SFTPB Sample Tissue: Human MCF7 Whole Cell Antibody Dilution: 1ug/ml |
|
Image 3 | Human Lung Tissue
| SFTPB antibody - middle region (ARP41411_P050)
Catalog Number: ARP41411_P050
Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue
Observed Staining: Cytoplasm and membrane of pneumocytes
Primary Antibody Concentration: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
|
Image 4 | Mouse Liver
| Host: Mouse Target Name: SFTPB Sample Tissue: Mouse Liver Antibody Dilution: 1ug/ml |
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