| Product Number |
ARP41102_T100 |
| Product Page |
www.avivasysbio.com/hnrpll-antibody-n-terminal-region-arp41102-t100.html |
| Name |
HNRPLL Antibody - N-terminal region (ARP41102_T100) |
| Protein Size (# AA) |
542 amino acids |
| Molecular Weight |
60kDa |
| NCBI Gene Id |
92906 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Heterogeneous nuclear ribonucleoprotein L-like |
| Alias Symbols |
SRRF, HNRPLL |
| Peptide Sequence |
Synthetic peptide located within the following region: RLKTEEGEIDYSAEEGENRREATPRGGGDGGGGGRSFSQPEAGGSHHKVS |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Shur,I., Gene 334, 113-121 (2004) |
| Description of Target |
HNRPLL contains 3 RRM (RNA recognition motif) domains and may bind RNA and plays a role in mRNA processing. |
| Protein Interactions |
HNRNPK; HNRNPLL; RHOXF2; BOLL; THAP1; RBPMS; QKI; UBE2I; MDFI; DAB1; UBC; ATXN1; PAXIP1; BARD1; CNOT3; PCBP1; SUMO2; VHL; PSMA3; HDAC5; DDX39B; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-HNRNPLL (ARP41102_T100) antibody |
| Blocking Peptide |
For anti-HNRNPLL (ARP41102_T100) antibody is Catalog # AAP41102 (Previous Catalog # AAPS02211) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human HNRPLL |
| Uniprot ID |
Q8WVV9 |
| Protein Name |
Heterogeneous nuclear ribonucleoprotein L-like |
| Publications |
Heyd, F. & Lynch, K. W. Phosphorylation-dependent regulation of PSF by GSK3 controls CD45 alternative splicing. Mol. Cell 40, 126-37 (2010). 20932480
Liu, G., Lei, L., Yu, J., Kung, S. & Xie, J. Refinement of the spectra of exon usage by combined effects of extracellular stimulus and intracellular factors. Biochim. Biophys. Acta 1839, 537-45 (2014). 24844182
Rajan, P. et al. Proteomic identification of heterogeneous nuclear ribonucleoprotein L as a novel component of SLM/Sam68 Nuclear Bodies. BMC Cell Biol. 10, 82 (2009). 19912651
Yu, J. et al. The heterogeneous nuclear ribonucleoprotein L is an essential component in the Ca2+/calmodulin-dependent protein kinase IV-regulated alternative splicing through cytidine-adenosine repeats. J. Biol. Chem. 284, 1505-13 (2009). 19017650 |
| Protein Accession # |
NP_612403 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_138394 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
HNRNPLL |
| Predicted Species Reactivity |
Human, Cow, Dog, Guinea Pig, Rabbit |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Human: 100%; Rabbit: 100% |
| Image 1 | Human HepG2
 | WB Suggested Anti-HNRPLL Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysate |
|
| Image 2 | Human Heart
 | Rabbit Anti-HNRPLL Antibody
Catalog Number: ARP41102
Paraffin Embedded Tissue: Human Heart
Cellular Data: Myocardial cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 3 | Human lung
 | Rabbit Anti-HNRPLL Antibody
Catalog Number: ARP41102
Paraffin Embedded Tissue: Human Lung
Cellular Data: Alveolar cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 4 | HepG2
 | Host: Rabbit
Target Name: HNRPLL
Sample Type: HepG2
Lane A: Primary Antibody
Lane B: Primary Antibody + Blocking Peptide
Primary Antibody Concentration: 2.5ug/mL
Peptide Concentration: 2.0ug/mL
Lysate Quantity: 25ug/lane
Gel Concentration: 12% |
|
