| Product Number |
ARP40922_T100 |
| Product Page |
www.avivasysbio.com/matr3-antibody-n-terminal-region-arp40922-t100.html |
| Name |
MATR3 Antibody - N-terminal region (ARP40922_T100) |
| Protein Size (# AA) |
847 amino acids |
| Molecular Weight |
93kDa |
| NCBI Gene Id |
9782 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Matrin 3 |
| Alias Symbols |
MPD2, ALS21, VCPDM |
| Peptide Sequence |
Synthetic peptide located within the following region: MSKSFQQSSLSRDSQGHGRDLSAAGIGLLAAATQSLSMPASLGRMNQGTA |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Beausoleil,S.A., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 |
| Description of Target |
MATR3 is localized in the nuclear matrix. It may play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network.The protein encoded by this gene is localized in the nuclear matrix. It may play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. Two transcript variants encoding the same protein have been identified for this gene. |
| Protein Interactions |
RASD1; MATR3; UBC; HNRNPK; CEP250; AURKA; SUMO2; SUMO3; STAU1; LGR4; SUMO1; MDM2; RPA3; RPA2; RPA1; ERG; WWOX; EED; rev; PARK2; TARDBP; PAN2; ITGA4; IFIT2; FN1; MAP1LC3A; PTBP2; vpr; MAGOH; EIF4A3; PRKCDBP; NAA15; IARS2; SMU1; SARS2; STOML2; RRP7A; MYOF; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-MATR3 (ARP40922_T100) antibody |
| Blocking Peptide |
For anti-MATR3 (ARP40922_T100) antibody is Catalog # AAP40922 (Previous Catalog # AAPP22890) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human MATR3 |
| Uniprot ID |
P43243 |
| Protein Name |
Matrin-3 |
| Publications |
Kula, A. et al. Characterization of the HIV-1 RNA associated proteome identifies Matrin 3 as a nuclear cofactor of Rev function. Retrovirology 8, 60 (2011). 21771346
Kula, A., Gharu, L. & Marcello, A. HIV-1 pre-mRNA commitment to Rev mediated export through PSF and Matrin 3. Virology 435, 329-40 (2013). 23158102
Valencia, C. A., Ju, W. & Liu, R. Matrin 3 is a Ca2+/calmodulin-binding protein cleaved by caspases. Biochem. Biophys. Res. Commun. 361, 281-6 (2007). 17658460 |
| Sample Type Confirmation |
MATR3 is strongly supported by BioGPS gene expression data to be expressed in Jurkat |
| Protein Accession # |
NP_061322 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_018834 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
MATR3 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93% |
| Image 1 | Human Heart
 | Rabbit Anti-MATR3 Antibody
Catalog Number: ARP40922
Paraffin Embedded Tissue: Human Heart
Cellular Data: Myocardial cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 2 | Human Muscle
 | Rabbit Anti-MATR3 Antibody
Catalog Number: ARP40922
Paraffin Embedded Tissue: Human Muscle
Cellular Data: Skeletal muscle cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 3 | Human Heart
 | Rabbit Anti-MATR3 Antibody
Catalog Number: ARP40922
Paraffin Embedded Tissue: Human cardiac cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 4 | Human Jurkat
 | WB Suggested Anti-MATR3 Antibody Titration: 1.25ug/ml
Positive Control: Jurkat cell lysateMATR3 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells |
|
