| Product Number |
ARP40230_P050 |
| Product Page |
www.avivasysbio.com/exosc3-antibody-c-terminal-region-arp40230-p050.html |
| Name |
EXOSC3 Antibody - C-terminal region (ARP40230_P050) |
| Protein Size (# AA) |
164 amino acids |
| Molecular Weight |
17kDa |
| NCBI Gene Id |
51010 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Exosome component 3 |
| Alias Symbols |
p10, PCH1B, RRP40, Rrp40p, CGI-102, hRrp-40, bA3J10.7 |
| Peptide Sequence |
Synthetic peptide located within the following region: VIGIVTAKSGDIFKVDVGGSEPASLSYLSFEGATKRNRPNVQAISSRL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Lehner,B. (2004) Genome Res. 14 (7), 1315-1323 |
| Description of Target |
EXOSC3 is component of the exosome 3'->5' exoribonuclease complex and is required for the 3' processing of the 7S pre-RNA to the mature 5.8S rRNA. |
| Protein Interactions |
UBC; EXOSC5; EXOSC4; CDK5RAP1; EXOSC8; ATP5D; AICDA; EXOSC10; EXOSC9; APP; EXOSC2; EXOSC6; DIS3L; EXOSC1; EXOSC3; EXOSC7; DIS3; MPHOSPH6; HDGF; KHSRP; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-EXOSC3 (ARP40230_P050) antibody |
| Blocking Peptide |
For anti-EXOSC3 (ARP40230_P050) antibody is Catalog # AAP40230 (Previous Catalog # AAPP22074) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human EXOSC3 |
| Uniprot ID |
Q9NQT5 |
| Protein Name |
Exosome complex component RRP40 |
| Publications |
Fan, M.-J. et al. Reduction of TLR4 mRNA stability and protein expressions through inhibiting cytoplasmic translocation of HuR transcription factor by Eâ and/or ERa in LPS-treated H9c2 cardiomyoblast cells. Chin. J. Physiol. 57, 8-18 (2014). 24621334 |
| Protein Accession # |
NP_001002269 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_001002269 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
EXOSC3 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 91%; Zebrafish: 100% |
| Image 1 | Human Placenta
 | WB Suggested Anti-EXOSC3 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Placenta |
|
