| Product Number |
ARP39519_P050 |
| Product Page |
www.avivasysbio.com/foxm1-antibody-middle-region-arp39519-p050.html |
| Name |
FOXM1 Antibody - middle region (ARP39519_P050) |
| Protein Size (# AA) |
763 amino acids |
| Molecular Weight |
84kDa |
| NCBI Gene Id |
2305 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Forkhead box M1 |
| Alias Symbols |
MPP2, HFH11, HNF-3, INS-1, MPP-2, PIG29, FKHL16, FOXM1A, FOXM1B, FOXM1C, HFH-11, TRIDENT, MPHOSPH2 |
| Peptide Sequence |
Synthetic peptide located within the following region: ANRSLTEGLVLDTMNDSLSKILLDISFPGLDEDPLGPDNINWSQFIPELQ |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Laoukili,J., (2008) Mol. Cell. Biol. 28 (9), 3076-3087 |
| Description of Target |
This protein acts as a Transcriptional activatory factor. May play a role in the control of cell proliferation. |
| Protein Interactions |
SMAD3; FZR1; SUMO1; UBE2I; SP1; CDK2; CCNE1; BANP; OS9; HSP90AA1; CDK6; CDK4; DHX29; ACAT1; CDC27; UBC; BCL6; SUMO2; RB1; CREBBP; CDC25B; CDK1; CCNB1; ZBTB3; CHEK2; STAT3; CDH1; CENPF; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-FOXM1 (ARP39519_P050) antibody |
| Blocking Peptide |
For anti-FOXM1 (ARP39519_P050) antibody is Catalog # AAP39519 (Previous Catalog # AAPP21535) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human FOXM1 |
| Uniprot ID |
Q08050 |
| Protein Name |
Forkhead box protein M1 |
| Publications |
Hu, C. et al. LXRa-mediated downregulation of FOXM1 suppresses the proliferation of hepatocellular carcinoma cells. Oncogene (2013). doi:10.1038/onc.2013.250 23812424 |
| Protein Accession # |
NP_068772 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_021953 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
FOXM1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Dog, Guinea Pig, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Dog: 79%; Guinea Pig: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93% |
| Image 1 | Transfected 293T
 | WB Suggested Anti-FOXM1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Transfected 293T |
|
| Image 2 | Human
 | Lanes:
Lane 1: 25ug MIA PaCa-2 human pancreatic cancer cell line)
Lane 2: 25ug MDA-MB-231 cell lysate
Lane 3: 25ug Huh-7 cell lysate
Primary Antibody Dilution:
1:2000
Secondary Antibody:
Anti-rabbit-HRP
Secondary Antibody Dilution:
1:5000
Gene Name:
FOXM1
Submitted by:
Andrei L. Gartel, University of Illinois at Chicago
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