| Product Number |
ARP38224_P050-FITC |
| Product Page |
www.avivasysbio.com/smarce1-antibody-n-terminal-region-fitc-arp38224-p050-fitc.html |
| Name |
SMARCE1 Antibody - N-terminal region : FITC (ARP38224_P050-FITC) |
| Protein Size (# AA) |
411 amino acids |
| Molecular Weight |
47kDa |
| Conjugation |
FITC: Fluorescein Isothiocyanate |
| NCBI Gene Id |
6605 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 |
| Alias Symbols |
CSS5, BAF57 |
| Peptide Sequence |
Synthetic peptide located within the following region: MSKRPSYAPPPTPAPATQMPSTPGFVGYNPYSHLAYNNYRLGGNPGTNSR |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
| Reference |
Chen,J. (2005) Mol. Cell. Biol. 25 (20), 9016-9027 |
| Description of Target |
SMARCE1 is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. |
| Protein Interactions |
NOTCH2NL; KRTAP10-9; CCDC172; NBPF22P; TXLNA; MIPOL1; KRT40; MRFAP1L1; SYCE1; ING5; USHBP1; CEP70; CEP63; CCDC136; RINT1; TRIM54; AMOTL2; MED4; TFIP11; NUP62; MTUS2; EXOC7; RALBP1; SPAG5; JAKMIP2; TRIP10; STX11; CEP170P1; MEOX2; KRT31; KRT15; KIFC3; GOLGA |
| Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Datasheets/Manuals |
Printable datasheet for anti-SMARCE1 (ARP38224_P050-FITC) antibody |
| Blocking Peptide |
For anti-SMARCE1 (ARP38224_P050-FITC) antibody is Catalog # AAPS05009 |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human SMARCE1 |
| Uniprot ID |
Q969G3 |
| Protein Name |
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 |
| Sample Type Confirmation |
SMARCE1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat |
| Protein Accession # |
NP_003070 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_003079 |
| Gene Symbol |
SMARCE1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
| Image 1 | |
