PDX1 Peptide - middle region (AAP87020)

Data Sheet
 
Sku AAP87020
Price 99
Name PDX1 Peptide - middle region (AAP87020)
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Size 100ug
Gene PDX1
Alias symbols GSF, IPF1, IUF1, IDX-1, MODY4, PDX-1, STF-1, PAGEN1
Gene id 3651
Description of target The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Swissprot id P52945
Protein accession num NP_000200.1
Nucleotide accession num NM_000209.3
Protein size 283 amino acids
Molecular weight 31 kDa
Species reactivity Human
Peptide sequence Synthetic peptide located within the following region: KEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEEDKKRGGG
Quality control The peptide is characterized by mass spectroscopy
Description This is a synthetic peptide designed for use in combination with anti- PDX1 Antibody (ARP87020_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery International: 3-5 business days
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