Sku |
AAP87020 |
Price |
99 |
Name |
PDX1 Peptide - middle region (AAP87020) |
Purchase info |
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|
Size |
100ug |
Gene |
PDX1 |
Alias symbols |
GSF, IPF1, IUF1, IDX-1, MODY4, PDX-1, STF-1, PAGEN1 |
Gene id |
3651 |
Description of target |
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). |
Swissprot id |
P52945 |
Protein accession num |
NP_000200.1 |
Nucleotide accession num |
NM_000209.3 |
Protein size |
283 amino acids |
Molecular weight |
31 kDa |
Species reactivity |
Human |
Peptide sequence |
Synthetic peptide located within the following region: KEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEEDKKRGGG |
Quality control |
The peptide is characterized by mass spectroscopy |
Description |
This is a synthetic peptide designed for use in combination with anti- PDX1 Antibody (ARP87020_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |