| Sku |
AAP63180 |
| Price |
$99.00 |
| Name |
NF2 Peptide - C-terminal region (AAP63180) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100ug |
| Gene |
NF2 |
| Alias symbols |
ACN, BANF, SCH |
| Gene id |
4771 |
| Description of target |
This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. |
| Swissprot id |
P35240-4 |
| Protein accession num |
NP_861968 |
| Nucleotide accession num |
NM_181830 |
| Protein size |
507 amino acids |
| Molecular weight |
56kDa |
| Species reactivity |
Human |
| Application |
WB |
| Peptide sequence |
MAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPA |
| Partner proteins |
EZR,HGS,NF2,PAK1,SDCBP,SLC9A3R1,TARBP2,TSC1,CD44,CTNNB1,ERBB2,EZR,HGS,ITGB1,NF2,PAK1,PXN,RALGDS,SCHIP1,SDCBP,SGSM3,SLC9A3R1,SPTBN1,TARBP2,TSC1,XPO1,AGAP2,AKT1,AMOT,ARHGAP32,CD44,CUL4A,DDB1,EZR,HGS,MED28,NF2,PXN,PYGO2,RIT1,SCHIP1,SDCBP,SGSM3,SLC9A3R1,SOS1, |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
N/A |
| Description |
This is a synthetic peptide designed for use in combination with anti-NF2 Antibody (ARP63180_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
