CAPZA3 Peptide - N-terminal region (AAP58604)

Data Sheet
 
Sku AAP58604
Old sku AAPP35741
Price $99.00
Name CAPZA3 Peptide - N-terminal region (AAP58604)
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Size 100 ug
Gene CAPZA3
Alias symbols CAPPA3, Gsg3
Gene id 93661
Description of target F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. CAPZA3 may play a role in the morphogenesis of spermatid.This gene encodes an actin capping protein, one of the F-actin capping protein alpha subunit family. The encoded protein is predominantly localized to the neck region of ejaculated sperm, other immunohistochemical signals were found in the tail and postacrosomal regions. The encoded protein may also form heterodimers of alpha and beta subunits. This protein may be important in determining sperm architecture and male fertility.
Swissprot id Q96KX2
Protein accession num NP_201585
Nucleotide accession num NM_033328
Protein size 299 amino acids
Molecular weight 33kDa
Application WB
Partner proteins ACTG1,CAPZA2
Subunit alpha-3
Quality control The peptide is characterized by mass spectroscopy
Key reference Miyagawa,Y., (2002) Mol. Hum. Reprod. 8 (6), 531-539
Description This is a synthetic peptide designed for use in combination with anti-CAPZA3 antibody (Catalog #: ARP58604_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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