Sku |
AAP54322 |
Old sku |
AAPP31070 |
Price |
$99.00 |
Name |
IL1A Peptide (AAP54322) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
IL1A |
Alias symbols |
IL-1A, IL1, IL1-ALPHA, IL1F1 |
Gene id |
3552 |
Description of target |
The IL1A protein is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. The gene encoding IL1A and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Swissprot id |
P01583 |
Protein accession num |
NP_000566 |
Nucleotide accession num |
NM_000575 |
Protein size |
271 amino acids |
Molecular weight |
18kDa |
Application |
WB |
Partner proteins |
HAX1,CAPN1,HAX1,IL1A,IL1R1,IL1R2,IL1RAP,NDN,NFKBIE,S100A13,HAX1,IL1A,NDN,S100A13 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Ikeda,S., (2008) Am. J. Gastroenterol. 103 (6), 1476-1487 |
Description |
This is a synthetic peptide designed for use in combination with anti-IL1A antibody (Catalog #: ARP54322_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |