IL1A Peptide (AAP54322)

Data Sheet
 
Sku AAP54322
Old sku AAPP31070
Price $99.00
Name IL1A Peptide (AAP54322)
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Size 100 ug
Gene IL1A
Alias symbols IL-1A, IL1, IL1-ALPHA, IL1F1
Gene id 3552
Description of target The IL1A protein is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. The gene encoding IL1A and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot id P01583
Protein accession num NP_000566
Nucleotide accession num NM_000575
Protein size 271 amino acids
Molecular weight 18kDa
Application WB
Partner proteins HAX1,CAPN1,HAX1,IL1A,IL1R1,IL1R2,IL1RAP,NDN,NFKBIE,S100A13,HAX1,IL1A,NDN,S100A13
Quality control The peptide is characterized by mass spectroscopy
Key reference Ikeda,S., (2008) Am. J. Gastroenterol. 103 (6), 1476-1487
Description This is a synthetic peptide designed for use in combination with anti-IL1A antibody (Catalog #: ARP54322_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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