Sku |
AAP51775 |
Old sku |
AAPY03509 |
Price |
$99.00 |
Name |
DCK Peptide - middle region (AAP51775) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
DCK |
Alias symbols |
MGC117410, MGC138632 |
Gene id |
1633 |
Description of target |
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Swissprot id |
P27707 |
Protein accession num |
NP_000779 |
Nucleotide accession num |
NM_000788 |
Protein size |
260 amino acids |
Molecular weight |
30kDa |
Application |
WB |
Partner proteins |
DDX19B,GOLM1,MED19,DDX19B,GOLM1,MED19 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Iyidogan,P. (2008) Biochemistry 47 (16), 4711-4720 |
Description |
This is a synthetic peptide designed for use in combination with anti-DCK antibody (Catalog #: ARP51775_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |