TUSC4 Peptide - N-terminal region (AAP50539)

Data Sheet
 
Sku AAP50539
Old sku AAPY02471
Price $99.00
Name TUSC4 Peptide - N-terminal region (AAP50539)
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Size 100 ug
Gene NPRL2
Alias symbols NPR2L, NPRL2, NPR2, TUSC4
Gene id 10641
Description of target TUSC4 suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. TUSC4 down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. TUSC4 may act as a tumor suppressor. TUSC4 suppresses cell growth and enhanced sensitivity to various anticancer drugs.
Swissprot id Q8WTW4
Protein accession num NP_006536
Nucleotide accession num NM_006545
Protein size 380 amino acids
Molecular weight 44kDa
Application IHC, WB
Partner proteins UBC; HSP90AA1; CDKN1A; ANXA7; NPRL3; UBE2M; PRKAR1A;
Quality control The peptide is characterized by mass spectroscopy
Key reference Ewing,R.M., Mol. Syst. Biol. 3, 89 (2007)
Description This is a synthetic peptide designed for use in combination with anti-TUSC4 antibody (Catalog #: ARP50539_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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