| Sku |
AAP49154 |
| Old sku |
AAPY02354 |
| Price |
$99.00 |
| Name |
OGT Peptide (AAP49154) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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|
| Size |
100 ug |
| Gene |
OGT |
| Alias symbols |
FLJ23071, HRNT1, MGC22921, O-GLCNAC |
| Gene id |
8473 |
| Description of target |
OGT catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains nine tetratricopeptide repeats and a putative bipartite nuclear localization signal. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains nine tetratricopeptide repeats and a putative bipartite nuclear localization signal. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| Swissprot id |
O15294 |
| Protein accession num |
NP_858058 |
| Nucleotide accession num |
NM_181672 |
| Protein size |
1046 amino acids |
| Molecular weight |
117kDa |
| Application |
IHC, WB |
| Partner proteins |
CSNK2A1,GSK3B,HCFC1,MAPT,NUP62CL,OGT,SIN3A,SNAP91,SP1,SRF,TRAK1,TRAK2,BAP1,BTRC,CDK2,FBXW11,FIBP,HCFC1,NUP62CL,OGT,SIN3A,THAP1,THAP3,TRAK1,WDR8 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Taylor,R.P., (2008) J. Biol. Chem. 283 (10), 6050-6057 |
| Description |
This is a synthetic peptide designed for use in combination with anti-OGT antibody (Catalog #: ARP49154_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
