CD36 Peptide - N-terminal region (AAP48127)

Data Sheet
 
Sku AAP48127
Old sku AAPP28011
Price $99.00
Name CD36 Peptide - N-terminal region (AAP48127)
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Size 100 ug
Gene symbol CD36
Alias symbols CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3, BDPLT10
Gene id 948
Description of target CD36 is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in its gene cause platelet glycoprotein deficiency. The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Swissprot id P16671
Protein accession num NP_001001547
Nucleotide accession num NM_001001547
Protein size 472 amino acids
Molecular weight 53kDa
Application IHC, WB
Partner proteins CD9,COL1A1,COL1A2,FYN,ITGA2B,ITGA6,ITGB1,ITGB3,LYN,MATK,SRC,THBS1,YES1,CD9,FYN,HSD11B1,ITGA2B,ITGA6,ITGB1,ITGB3,LDLR,LYN,MATK,VLDLR,YES1
Quality control The peptide is characterized by mass spectroscopy
Key reference Bhr,C., (2008) Hum. Mol. Genet. 17 (11), 1695-1704
Description This is a synthetic peptide designed for use in combination with anti-CD36 antibody (Catalog #: ARP48127_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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