| Sku |
AAP46049 |
| Old sku |
AAPP26890 |
| Price |
$99.00 |
| Name |
PAICS Peptide (AAP46049) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
PAICS |
| Alias symbols |
ADE2, ADE2H1, AIRC, DKFZp781N1372, MGC1343, MGC5024, PAIS |
| Gene id |
10606 |
| Description of target |
PAICS is a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Swissprot id |
P22234 |
| Protein accession num |
NP_001072992 |
| Nucleotide accession num |
NM_001079524 |
| Protein size |
425 amino acids |
| Molecular weight |
47kDa |
| Application |
WB |
| Partner proteins |
STAU1,CEP76,CHD3,FXR2,LNX1,MOBKL3,NUDT18,PAICS,CEP76,CHD3,DGKE,EIF6,EPB41,FXR2,GNAS,HLA-B,LNX1,MCC,MOBKL3,NUDT18,PAICS,PSMC4,TRAF6 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Beausoleil,S.A., (2006) Nat. Biotechnol. 24 (10), 1285-1292 |
| Description |
This is a synthetic peptide designed for use in combination with anti-PAICS antibody (Catalog #: ARP46049_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
