| Sku |
AAP45601 |
| Old sku |
AAPP11880 |
| Price |
$99.00 |
| Name |
RARB Peptide (AAP45601) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
RARB |
| Alias symbols |
HAP, NR1B2, RRB2 |
| Gene id |
5915 |
| Description of target |
RARB is a retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants; one additional transcript has been described, but its full length nature has not been determined. |
| Swissprot id |
P10826 |
| Protein accession num |
NP_000956 |
| Nucleotide accession num |
NM_000965 |
| Protein size |
448 amino acids |
| Molecular weight |
50kDa |
| Application |
IHC, WB |
| Partner proteins |
DNMT1,DNMT3A,DNMT3B,HDAC1,HIST4H4,MAP6,NCOA1,NCOA3,NCOR2,PNRC1,RXRA,RXRB,RXRG,SMAD2,CEBPA,CEBPB,NCOA1,NR4A2 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Uhl,G.R., (2008) Arch. Gen. Psychiatry 65 (6), 683-693 |
| Description |
This is a synthetic peptide designed for use in combination with anti-RARB antibody (Catalog #: ARP45601_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
