CPT1A Peptide - middle region (AAP44796)

Data Sheet
 
Sku AAP44796
Old sku AAPP12272
Price $99.00
Name CPT1A Peptide - middle region (AAP44796)
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Size 100 ug
Gene CPT1A
Alias symbols CPT1, CPT1-L, L-CPT1
Gene id 1374
Description of target The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation.The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Swissprot id P50416
Protein accession num NP_001027017
Nucleotide accession num NM_001031847
Protein size 756 amino acids
Molecular weight 86kDa
Application IHC, WB
Partner proteins BCL2
Quality control The peptide is characterized by mass spectroscopy
Key reference Roomets,E., (2008) Invest. Ophthalmol. Vis. Sci. 49 (4), 1660-1664
Description This is a synthetic peptide designed for use in combination with anti-CPT1A antibody (Catalog #: ARP44796_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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