ECH1 Peptide (AAP43560)

Data Sheet
 
Sku AAP43560
Old sku AAPP25005
Price $99.00
Name ECH1 Peptide (AAP43560)
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Size 100 ug
Gene ECH1
Alias symbols HPXEL
Gene id 1891
Description of target ECH1 is a member of the hydratase/isomerase superfamily. ECH1 shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The protein contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway.This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.
Swissprot id Q13011
Protein accession num NP_001389
Nucleotide accession num NM_001398
Protein size 328 amino acids
Molecular weight 36kDa
Application WB
Partner proteins CSTF2,EEF1G,PAFAH1B3,SERPINB9,TIMP1,TLR10,CSTF2,EEF1G,PAFAH1B3,SERPINB9,TIMP1
Quality control The peptide is characterized by mass spectroscopy
Key reference Goehler,H., (2004) Mol. Cell 15 (6), 853-865
Description This is a synthetic peptide designed for use in combination with anti-ECH1 antibody (Catalog #: ARP43560_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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