| Sku |
AAP42788 |
| Old sku |
AAPS10202 |
| Price |
$99.00 |
| Name |
HDAC9 Peptide (AAP42788) |
| Purchase info |
To purchase this peptide:
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|
| Size |
100 ug |
| Gene |
HDAC9 |
| Alias symbols |
DKFZp779K1053, HD7, HDAC, HDAC7, HDAC7B, HDAC9B, HDAC9FL, HDRP, KIAA0744, MITR, HD9, HD7b |
| Gene id |
9734 |
| Description of target |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC9 has sequence homology to members of the histone deacetylase family. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. HDAC9 may play a role in hematopoiesis.Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined. |
| Swissprot id |
A7E2F3 |
| Protein accession num |
NP_055522 |
| Nucleotide accession num |
NM_014707 |
| Protein size |
590 amino acids |
| Molecular weight |
65kDa |
| Application |
CHIP, IHC, WB |
| Partner proteins |
BCL6,CBX5,CTBP1,ETV6,HDAC1,HDAC3,HDAC4,MEF2A,NCOR1,SIN3A,SIN3B,SUMO1,SUMO2,ZBTB16,CBX5,CTBP1,ETV6,FOXP3,HDAC1,HDAC1,HDAC3,HDAC3,HDAC4,HEY2,HIST2H3A,HIST4H4,MEF2A,MORF4L2,NCOR1,NRIP1,SIN3A,SIN3B,SUV39H1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Han,A., (2005) J. Mol. Biol. 345 (1), 91-102 |
| Description |
This is a synthetic peptide designed for use in combination with anti-HDAC9 antibody (Catalog #: ARP42788_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
