| Sku |
AAP41251 |
| Old sku |
AAPP22606 |
| Price |
$99.00 |
| Name |
FZD7 Peptide (AAP41251) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
FZD7 |
| Alias symbols |
FzE3 |
| Gene id |
8324 |
| Description of target |
FZD7 is 7-transmembrane domain protein that is receptor for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif.Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. |
| Swissprot id |
O75084 |
| Protein accession num |
NP_003498 |
| Nucleotide accession num |
NM_003507 |
| Protein size |
574 amino acids |
| Molecular weight |
63kDa |
| Application |
IHC, WB |
| Partner proteins |
DLG1,DLG2,DLG4,MAGI3,UBQLN1,UBQLN4,DLG4,UBQLN1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Vincan,E., (2005) Differentiation 73 (4), 142-153 |
| Description |
This is a synthetic peptide designed for use in combination with anti-FZD7 antibody (Catalog #: ARP41251_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
