| Sku |
AAP40238 |
| Old sku |
AAPP22082 |
| Price |
$99.00 |
| Name |
HNRPD Peptide - C-terminal region (AAP40238) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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|
| Size |
100 ug |
| Gene |
HNRNPD |
| Alias symbols |
P37, AUF1, AUF1A, HNRPD, hnRNPD0 |
| Gene id |
3184 |
| Description of target |
HNRPD belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants. |
| Swissprot id |
Q14103 |
| Protein accession num |
NP_112738 |
| Nucleotide accession num |
NM_031370 |
| Protein size |
355 amino acids |
| Molecular weight |
39kDa |
| Application |
IHC, WB |
| Partner proteins |
NCL; FUS; KAT2B; SUMO2; SUMO3; IVNS1ABP; STAU1; UBC; NEDD8; MDM2; ERG; RPA3; RPA2; RPA1; ASB2; EED; rev; ERI1; RPS12; PTBP1; PAFAH1B3; WNK1; IPO11; EIF3K; KHSRP; DENR; PARK2; DGCR2; GTF3C3; PDLIM7; UQCRC1; HIRA; SNAPC4; SLC3A2; SDF2; COG7; TMEM261; ABCC10 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Dhakras,P.S., Am. J. Physiol. Renal Physiol. 290 (2), F313-F318 (2006) |
| Description |
This is a synthetic peptide designed for use in combination with anti-HNRPD antibody (Catalog #: ARP40238_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
