CREB3 Peptide - middle region (AAP38790)

Data Sheet
 
Sku AAP38790
Old sku AAPP20995
Price $99.00
Name CREB3 Peptide - middle region (AAP38790)
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Size 100 ug
Gene CREB3
Alias symbols LUMAN, LZIP, MGC15333, MGC19782
Gene id 10488
Description of target CREB3 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot id O43889
Protein accession num NP_006359
Nucleotide accession num NM_006368
Protein size 371 amino acids
Molecular weight 41kDa
Application WB
Partner proteins APPBP2,BNIP2,CCR1,EMD,HCFC1,MALL,NFIL3,STX8,APPBP2,BNIP2,EMD,HCFC1,MALL,STX8
Quality control The peptide is characterized by mass spectroscopy
Key reference Mamdani,F., (er) Am. J. Med. Genet. B Neuropsychiatr. Genet. (2008) In press
Description This is a synthetic peptide designed for use in combination with anti-CREB3 antibody (Catalog #: ARP38790_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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