Sku |
AAP36407 |
Old sku |
AAPP08463 |
Price |
$99.00 |
Name |
RAD54B Peptide - N-terminal region (AAP36407) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
RAD54B |
Alias symbols |
FSBP, RDH54 |
Gene id |
25788 |
Description of target |
RAD54B belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer. |
Swissprot id |
Q9Y620 |
Protein accession num |
NP_036547 |
Nucleotide accession num |
NM_012415 |
Protein size |
910 amino acids |
Molecular weight |
103kDa |
Application |
IHC, WB |
Partner proteins |
DMC1,CCDC33,CDC23,CSNK1E,DMC1,DYRK2,GORASP2,LNX1,PSMA1,RAD51,RAD54B,RIBC2,TRAPPC6A,UBE2I,ZNF580,CCDC33,CD2BP2,CDC23,CSNK1E,DYRK2,GORASP2,LNX1,MYO15B,PSMA1,RAD51,RAD54B,RIBC2,TCEANC,TRAPPC6A,UBE2I,ZNF580 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Brys,M., (2007) Pol J Pathol 58 (1), 3-6 |
Description |
This is a synthetic peptide designed for use in combination with anti-RAD54B antibody (Catalog #: ARP36407_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |