EYA1 Peptide - middle region (AAP32434)

Data Sheet
 
Sku AAP32434
Old sku AAPP03430
Price $99.00
Name EYA1 Peptide - middle region (AAP32434)
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Size 100 ug
Gene EYA1
Alias symbols BOP, BOR, MGC141875
Gene id 2138
Description of target EYA1 is a member of the eyes absent (EYA) family of proteins. EYA1 may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator.This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator. Four transcript variants encoding three distinct isoforms have been identified for this gene.
Swissprot id Q99502
Protein accession num NP_742057
Nucleotide accession num NM_172060
Protein size 557 amino acids
Molecular weight 61kDa
Application IHC, WB
Partner proteins DACH1,GNAI2,GNAZ,SIX1,SIX2,SIX3,SIX1
Quality control The peptide is characterized by mass spectroscopy
Key reference Orten,D.J., (2008) Hum. Mutat. 29 (4), 537-544
Description This is a synthetic peptide designed for use in combination with anti-EYA1 antibody (Catalog #: ARP32434_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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