Sku |
AAP31932 |
Old sku |
AAPP02829 |
Price |
$99.00 |
Name |
CSEN Peptide - N-terminal region (AAP31932) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
KCNIP3 |
Alias symbols |
CSEN, DREAM, KCHIP3 |
Gene id |
30818 |
Description of target |
CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The protein encoded by this gene is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease. |
Swissprot id |
Q9Y2W7 |
Protein accession num |
NP_038462 |
Nucleotide accession num |
NM_013434 |
Protein size |
256 amino acids |
Molecular weight |
29kDa |
Application |
IHC, WB |
Partner proteins |
MAVS; CD177; IGLV3-25; IL6ST; IGF1R; KCND2; CLN3; CALM2; KCNIP3; PPP3CA; GRK6; ADRBK1; UBE2I; UBC; PCBD2; TARBP2; PSEN2; CASP3; CREM; CREB1; PSEN1; CRK; |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Zaidi,N.F., et al., (2004) J. Neurochem. 89 (3), 593-601 |
Description |
This is a synthetic peptide designed for use in combination with anti-CSEN antibody (Catalog #: ARP31932_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |