CSEN Peptide - N-terminal region (AAP31932)

Data Sheet
 
Sku AAP31932
Old sku AAPP02829
Price $99.00
Name CSEN Peptide - N-terminal region (AAP31932)
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Size 100 ug
Gene KCNIP3
Alias symbols CSEN, DREAM, KCHIP3
Gene id 30818
Description of target CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The protein encoded by this gene is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease.
Swissprot id Q9Y2W7
Protein accession num NP_038462
Nucleotide accession num NM_013434
Protein size 256 amino acids
Molecular weight 29kDa
Application IHC, WB
Partner proteins MAVS; CD177; IGLV3-25; IL6ST; IGF1R; KCND2; CLN3; CALM2; KCNIP3; PPP3CA; GRK6; ADRBK1; UBE2I; UBC; PCBD2; TARBP2; PSEN2; CASP3; CREM; CREB1; PSEN1; CRK;
Quality control The peptide is characterized by mass spectroscopy
Key reference Zaidi,N.F., et al., (2004) J. Neurochem. 89 (3), 593-601
Description This is a synthetic peptide designed for use in combination with anti-CSEN antibody (Catalog #: ARP31932_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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