| Sku |
AAP31220 |
| Price |
$99.00 |
| Name |
RARA Peptide - middle region (AAP31220) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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|
| Size |
100ug |
| Gene |
RARA |
| Alias symbols |
NR1B1, RAR |
| Gene id |
5914 |
| Description of target |
Retinoid signaling is transduced by 2 families of nuclear receptors, retinoic acid receptor (RAR) and retinoid X receptor, which form RXR/RAR heterodimers. In the absence of ligand, DNA-bound RXR/RARA represses transcription by recruiting the corepressors NCOR1, SMRT, and histone deacetylase. When ligand binds to the complex, it induces a conformational change allowing the recruitment of coactivators, histone acetyltransferases, and the basic transcription machinery. |
| Swissprot id |
P10276 |
| Protein accession num |
NP_000955 |
| Nucleotide accession num |
NM_000964 |
| Protein size |
393 amino acids |
| Molecular weight |
42kDa |
| Species reactivity |
Human |
| Application |
WB |
| Peptide sequence |
DPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLR |
| Partner proteins |
NCOR2; NCOR1; RXRG; MED1; HDAC1; NRIP1; TEKT4; NSD1; NCOA1; CEBPA; ITGB1BP2; SUMO1; UBC; MBD3; CBX5; MTA2; E2F1; WWOX; Sumo2; RXRB; RXRA; AKT1; MMS19; Dlg4; TMEM54; FN1; USP7; NCOA2; SUZ12; EZH2; PML; PSMC5; FAS; PRAM1; TBL1XR1; PRAME; ARID5A; UBE3A; UBQL |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
N/A |
| Description |
This is a synthetic peptide designed for use in combination with anti-PAX2 Antibody (ARP31220_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
