Sku |
AAP31156 |
Old sku |
AAPP01895 |
Price |
$99.00 |
Name |
NR2C1 Peptide (AAP31156) |
Purchase info |
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|
Size |
100 ug |
Gene |
NR2C1 |
Alias symbols |
TR2 |
Gene id |
7181 |
Description of target |
The nuclear orphan receptors NR2C1 represses transcription and binds DNA as a homodimer. NR2C1 binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. NR2C1 may function as a negative modulator to suppress androgen receptor function in prostate cancer. NR2C1 may exert an important repressor in regulating ER activity in mammary glands. The nuclear orphan receptors TR2 (NR2C1) and TR4 form a heterodimer that binds to the epsilon and gamma globin promoter DR1 sites |
Swissprot id |
Q15625 |
Protein accession num |
NP_003288 |
Nucleotide accession num |
NM_003297 |
Protein size |
603 amino acids |
Molecular weight |
67kDa |
Application |
WB |
Partner proteins |
AR,ESR1,HDAC3,HDAC4,NR2C2,NRIP1,AR,ESR1,HDAC3,HDAC4 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Li,G., et al., (2003) Biochem. Biophys. Res. Commun. 310 (2), 384-390 |
Description |
This is a synthetic peptide designed for use in combination with anti-NR2C1 antibody (Catalog #: P100812_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |