Sku |
AAP31132 |
Old sku |
AAPP01871 |
Price |
$99.00 |
Name |
RORA Peptide - N-terminal region (AAP31132) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
RORA |
Alias symbols |
MGC119326, MGC119329, NR1F1, ROR1, ROR2, ROR3, RZRA, RZR-ALPHA |
Gene id |
6095 |
Description of target |
RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene. |
Swissprot id |
B6ZGS4 |
Protein accession num |
NP_599023 |
Nucleotide accession num |
NM_134261 |
Protein size |
523 amino acids |
Molecular weight |
59kDa |
Application |
WB |
Partner proteins |
COPS5,EP300,LMO3,MED1,MYOD1,NCOA2,NME1,NME2,NR0B1,PNRC1,PNRC2,PROX1,PSMC5,RORA,SMARCD3,ZXDC,EP300,MYOD1,NME1,PSMC5 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Tordjman,J., (2007) J. Biol. Chem. 282 (32), 23591-23602 |
Description |
This is a synthetic peptide designed for use in combination with anti-RORA antibody (Catalog #: P100793_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |