| Sku |
AAP30933 |
| Old sku |
AAPP01657 |
| Price |
$99.00 |
| Name |
MAF Peptide - middle region (AAP30933) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
MAF |
| Alias symbols |
MGC71685, c-MAF |
| Gene id |
4094 |
| Description of target |
MAF acts as a transcriptional activator or repressor. It is involved in embryonic lens fiber cell development. It recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. MAF is also involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. When overexpressed, MAF represses anti-oxidant reponse element (ARE)-mediated transcription. It may be involved either as an oncogene or as a tumor suppressor, depending on the cell context. |
| Swissprot id |
O75444-1 |
| Protein accession num |
NP_005351 |
| Nucleotide accession num |
NM_005360 |
| Protein size |
403 amino acids |
| Molecular weight |
42kDa |
| Application |
WB |
| Partner proteins |
CREBBP,EP300,CREBBP,EP300,ETS1,FOS,JUN,MAF,MAFA,MAFG,MYB,SMARCA5,SOX9,USF2,CREBBP,EP300,ETS1,HOXD12,MAF,MAFG,MYB,SOX9,USF2 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Gosmain,Y., (2007) J. Biol. Chem. 282 (48), 35024-35034 |
| Description |
This is a synthetic peptide designed for use in combination with anti-MAF antibody (Catalog #: P100617_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
