| Sku |
AAP30774 |
| Old sku |
AAPP01437 |
| Price |
$99.00 |
| Name |
CCR8 Peptide (AAP30774) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
CCR8 |
| Alias symbols |
CY6, TER1, CCR-8, CKRL1, CDw198, CMKBR8, GPRCY6, CMKBRL2, CC-CKR-8 |
| Gene id |
1237 |
| Description of target |
CCR8 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. Its gene is located at the chemokine receptor gene cluster region. |
| Swissprot id |
P51685 |
| Protein accession num |
NP_005192 |
| Nucleotide accession num |
NM_005201 |
| Protein size |
355 amino acids |
| Molecular weight |
41kDa |
| Application |
WB |
| Partner proteins |
CCL1,CCL16,CCL17,CCL4,CCR8,TPST1,TPST2 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Haque,N.S., et al., (2004) Blood 103 (4), 1296-1304 |
| Description |
This is a synthetic peptide designed for use in combination with anti-CCR8 antibody (Catalog #: AVARP09059_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
