| Sku |
AAP30459 |
| Old sku |
AAPP01043 |
| Price |
$99.00 |
| Name |
MAPK14 Peptide (AAP30459) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
MAPK14 |
| Alias symbols |
RK, p38, CSBP, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, SAPK2A, p38ALPHA |
| Gene id |
1432 |
| Description of target |
MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Swissprot id |
Q16539 |
| Protein accession num |
NP_001306 |
| Nucleotide accession num |
NM_001315 |
| Protein size |
360 amino acids |
| Molecular weight |
41kDa |
| Application |
IHC, WB |
| Partner proteins |
CDC25B,NCF1C,ATF2,BCL2,CDC25B,CDC25C,CDX2,CREB1,CSNK2A2,CSNK2B,DDIT3,DUSP1,DUSP10,DUSP16,DUSP2,DUSP22,DUSP4,DUSP7,DUSP9,DYRK1B,EEA1,EEF2K,EIF4EBP1,ELK1,ELK3,ESR1,FAM48A,FKBP8,FLNA,GADD45A,GMFB,GRB2,HNF4A,HSF4,HTRA2,IRAK1,JDP2,JUNB,KRT18,KRT8,MAFA,MAP2K1,MAP2K3,MAP2K4,MAP2K6,MAP3K7,MAPK1,MAPK3,MAPK8,MAPKAPK2,MAPKAPK3,MAPKAPK5,MAX,MBP,MEF2A,MEF2C,MITF,MKNK1,MKNK2,NCF1,NCOA3,NFATC1,NFATC4,NUP153,PLA2G4A,PML,PPARGC1A,PTPN7,RET,RPS6KA4,SCN8A,SHC1,SLC9A1,SMAD3,SMAD7,SPAG9,STAT1,STAT4,STK39,TAB1,TRAF6,ZFP36L1,ZFYVE20,ZNHIT1,AKT1,ATF2,ATF2,ATF2,ATF2,CDC25A,CDC25B,CDC25C,CSNK2A1,DDIT3,DUSP1,DUSP10,DUSP10,DUSP16,DUSP4,DUSP6,DYRK1B,EGFR,ELK1,ELK1,ELK4,ELK4,ETV1,FUBP1,GMFB,HTRA2,JUN,KARS,KRT8,MAP2K3,MAP2K3,MAP2K6,MAP2K7,MAPK1,MAPK14,MAPK3,MAPKAPK2,MAPKAPK3,MEF2A,MKNK1,MKNK1,PLCB2,RPS6KA3,RPS6KA4,RPS6KA5,Rps6kb1,SLC12A2,SMAD7,SPAG9,STK39,TAB1,TAB1,TGFBR1,ZFP36L1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Aleman,M., et al., (2004) Infect. Immun. 72 (9), 5150-5158 |
| Description |
This is a synthetic peptide designed for use in combination with anti-MAPK14 antibody (Catalog #: AVARP06004_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
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