IGF1R Peptide - middle region (AAP30448)

Data Sheet
 
Sku AAP30448
Old sku AAPP01032
Price $99.00
Name IGF1R Peptide - middle region (AAP30448)
Purchase info To purchase this peptide:
  • Copy peptide sku
  • Click on this link
  • Paste into field "Peptide Sku"
Size 100 ug
Gene IGF1R
Alias symbols CD221, IGFIR, JTK13, MGC142170, MGC142172, MGC18216, IGFR
Gene id 3480
Description of target This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-140 DR007209.1 566-705 141-3559 X04434.1 136-3554 3560-4540 BC113610.1 3542-4522 4541-4921 DA486252.1 187-567 4922-5392 BX093045.1 248-718 5393-5768 CN414655.1 317-692 5769-6158 BM264223.1 185-574 6159-6580 BQ185364.1 187-608 6581-11242 AC069029.9 21278-25939 c
Swissprot id P08069
Protein accession num NP_000866
Nucleotide accession num NM_000875
Protein size 1367 amino acids
Molecular weight 71kDa
Application IHC, WB
Partner proteins CSK,EHD1,GNB2L1,GRB10,IRS1,IRS1,IRS2,ITGB1,JAK1,PIK3R2,PRKCD,PRKD1,SHC1,SOCS1,SOCS2,SOCS3,YWHAB,YWHAE,YWHAZ,ARHGEF12,CRK,CRKL,CSK,DOK4,DOK5,EHD1,ESR1,GIPC1,GNAI1,GNAI2,GNB2L1,GRB10,IGF1,IGF1R,IGF2,IGFBP3,INS,INSR,IRS1,IRS2,IRS4,ITGB1,JAK1,JAK2,KL,KRT27,MAP3K5,MDM2,NEDD4,PIK3R1,PIK3R2,PIK3R3,PRKCD,PRKD1,PTPN1,PTPN11,RASA1,SOCS1,SOCS2,SOCS3,SRC,STAT3,VAV3,WISP2,YWHAB,YWHAE,YWHAG,YWHAZ,ARHGEF12,CBL,CSK,EEA1,EGFR,EHD1,ESR1,GNAI1,GNB2L1,GRB10,IGF1,IGFBP3,IRS1,JAK1,MDM2,NEDD4,PIK3R3,PTK2,PTPN1,PTPN11,PXN,RASA1,SHC1,SNAP29,SOCS1,SOCS2,SOCS3,UBC,VAV3,YWHAB,YWHAE,YWHAG
Quality control The peptide is characterized by mass spectroscopy
Key reference Urano,T., (2008) Spine 33 (11), 1256-1261
Description This is a synthetic peptide designed for use in combination with anti-IGF1R antibody (Catalog #: AVARP00004_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
Protocol
Tips

See our General FAQ page.
Availability In Stock
 

AVIVA SYSTEMS BIOLOGY manufactures and sells quality antibody products covering genome wide proteins.

This product is for Research Use Only. Not for diagnostic, human, or veterinary use.
Optimal conditions of its use should be determined by end users.

AVIVA SYSTEMS BIOLOGY
6370 Nancy Ridge Dr., Suite 104, San Diego, CA 92121 USA | Tel: (858)552-6979 | info@avivasysbio.com