BAX Peptide (AAP30231)

Data Sheet
 
Sku AAP30231
Old sku AAPP00401
Price $99.00
Name BAX Peptide (AAP30231)
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Size 100 ug
Gene BAX
Alias symbols BCL2L4
Gene id 581
Description of target BAX encodes a protein that belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. BAX expression is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis.
Swissprot id Q07812
Protein accession num NP_620116
Nucleotide accession num NM_138761
Protein size 192 amino acids
Molecular weight 21kDa
Application IHC, WB
Partner proteins TP53,TP53,TP73,BBC3,BCL2,BCL2,BCL2L1,BCL2L1,BID,MOAP1,NOL3,BAK1,BBC3,BCL2,BCL2A1,BCL2L1,BCL2L10,BID,ERN1,KCNA3,MCL1,MOAP1,NOL3,PMAIP1,PPP1CA,SFN,SH3GLB1,SLC25A4,VDAC1,YWHAQ,GTF2B,MUC1,TAF1,TBP,TP53,BAK1,BAX,BCL2,BCL2A1,BCL2L1,BCL2L1,BCL2L10,BCL2L2,BNIPL,Bak1,CRYAA,CRYAB,HSPD1,MCL1,MEPCE,MOAP1,MOAP1,OYE2,PMAIP1,SH3GLB1,SH3GLB1,SLC25A4,SNCA,TOMM22,TOMM40,UBC,VDAC1,YWHAQ
Quality control The peptide is characterized by mass spectroscopy
Key reference Yamaguchi,H., et al., (2004) J. Biol. Chem. 279 (38), 39431-39437
Description This is a synthetic peptide designed for use in combination with anti-BAX antibody (Catalog #: AVARP02020_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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AVIVA SYSTEMS BIOLOGY manufactures and sells quality antibody products covering genome wide proteins.

This product is for Research Use Only. Not for diagnostic, human, or veterinary use.
Optimal conditions of its use should be determined by end users.

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