| Sku |
AAP30150 |
| Old sku |
AAPP00307 |
| Price |
$99.00 |
| Name |
CDC25C Peptide - N-terminal region (AAP30150) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
CDC25C |
| Alias symbols |
CDC25, PPP1R60 |
| Gene id |
995 |
| Description of target |
CDC25C gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. |
| Swissprot id |
P30307 |
| Protein accession num |
NP_073720 |
| Nucleotide accession num |
NM_022809 |
| Protein size |
400 amino acids |
| Molecular weight |
45kDa |
| Application |
WB |
| Partner proteins |
SP1,TP53,BRSK1,BRSK2,CCNA2,CCNB1,CDK1,CHEK1,CHEK2,HRAS,LCK,LZTS1,MAPK14,MARK3,NEDD4,PCNA,PIN1,PKN1,PLK1,PLK3,TP53,YWHAB,YWHAH,YWHAQ,YWHAZ,CCNB1,CDK1,CHEK1,CHEK1,MAPK14,NEDD4,PCNA,PIN1,PLK1,PLK1,PLK3,SRC,YWHAB,YWHAE,YWHAH |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Bonnet,J., (2008) Biochem. Biophys. Res. Commun. 370 (3), 483-488 |
| Description |
This is a synthetic peptide designed for use in combination with anti-CDC25C antibody (Catalog #: AVARP03034_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
