Sku |
AAP30149 |
Old sku |
AAPP00306 |
Price |
$99.00 |
Name |
CDC25B Peptide (AAP30149) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
CDC25B |
Gene id |
994 |
Description of target |
CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. |
Swissprot id |
P30305 |
Protein accession num |
NP_068659 |
Nucleotide accession num |
NM_021873 |
Protein size |
580 amino acids |
Molecular weight |
65kDa |
Application |
IHC, WB |
Partner proteins |
AR,AURKA,BRSK1,BRSK2,CDK1,CHEK1,CREBBP,CSNK2A1,CSNK2B,ESR1,FHL3,KAT2B,MAPK14,MAPK14,MAPKAPK2,MELK,SFN,YWHAB,YWHAE,YWHAH,YWHAQ,YWHAZ,YWHAZ,AR,CDK2,CHEK1,CSNK2A1,ESR1,FBXW11,KAT2B,KRT31,KRT35,KRT85,MAPK14,MELK,PGR,PHB2,YWHAB,YWHAB,YWHAE,YWHAE,YWHAH,YWHAQ,YWHAZ |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Uchida,S., et al., (2004) Biochem. Biophys. Res. Commun. 316 (1), 226-232 |
Description |
This is a synthetic peptide designed for use in combination with anti-CDC25B antibody (Catalog #: AVARP03041_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |