CDC25B Peptide (AAP30149)

Data Sheet
 
Sku AAP30149
Old sku AAPP00306
Price $99.00
Name CDC25B Peptide (AAP30149)
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Size 100 ug
Gene CDC25B
Gene id 994
Description of target CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined.
Swissprot id P30305
Protein accession num NP_068659
Nucleotide accession num NM_021873
Protein size 580 amino acids
Molecular weight 65kDa
Application IHC, WB
Partner proteins AR,AURKA,BRSK1,BRSK2,CDK1,CHEK1,CREBBP,CSNK2A1,CSNK2B,ESR1,FHL3,KAT2B,MAPK14,MAPK14,MAPKAPK2,MELK,SFN,YWHAB,YWHAE,YWHAH,YWHAQ,YWHAZ,YWHAZ,AR,CDK2,CHEK1,CSNK2A1,ESR1,FBXW11,KAT2B,KRT31,KRT35,KRT85,MAPK14,MELK,PGR,PHB2,YWHAB,YWHAB,YWHAE,YWHAE,YWHAH,YWHAQ,YWHAZ
Quality control The peptide is characterized by mass spectroscopy
Key reference Uchida,S., et al., (2004) Biochem. Biophys. Res. Commun. 316 (1), 226-232
Description This is a synthetic peptide designed for use in combination with anti-CDC25B antibody (Catalog #: AVARP03041_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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