TRIM3 Antibody - N-terminal region (ARP34698_T100)

Data Sheet
 
Product Number ARP34698_T100
Product Page www.avivasysbio.com/trim3-antibody-n-terminal-region-arp34698-t100.html
Name TRIM3 Antibody - N-terminal region (ARP34698_T100)
Protein Size (# AA) 744 amino acids
Molecular Weight 81kDa
NCBI Gene Id 10612
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Tripartite motif containing 3
Alias Symbols BERP, HAC1, RNF22, RNF97
Peptide Sequence Synthetic peptide located within the following region: TICGAKQKVLQSQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHM
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Reymond,A., et al., (2001) EMBO J. 20 (9), 2140-2151
Description of Target The protein encoded by TRIM3 is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport.
Protein Interactions CUL3; UBC; HECW2; KIF21B; TNFAIP3; HGS; MYO5A; ACTN4; UBE2D4; UBE2U; UBE2G2; TRIM3; UBE2K;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-TRIM3 (ARP34698_T100) antibody
Blocking Peptide For anti-TRIM3 (ARP34698_T100) antibody is Catalog # AAP34698 (Previous Catalog # AAPP05888)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM3
Uniprot ID Q6ZTE7
Protein Name cDNA FLJ44731 fis, clone BRACE3025719, highly similar to Homo sapiens ring finger protein 22 (RNF22) EMBL BAC86643.1
Protein Accession # NP_006449
Purification Protein A purified
Nucleotide Accession # NM_006458
Tested Species Reactivity Human
Gene Symbol TRIM3
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 93%; Zebrafish: 92%
Image 1
Human kidney
Human kidney
Image 2
Human HepG2
WB Suggested Anti-TRIM3 Antibody Titration: 1.0ug/ml
ELISA Titer: 1:1562500
Positive Control: HepG2 cell lysate
 

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