TNFRSF10A Antibody - C-terminal region (ARP30622_P050)

• Product Number: ARP30622_P050
• Name: TNFRSF10A Antibody - C-terminal region (ARP30622_P050)
• Protein Size (# AA): 468 amino acids
• Molecular Weight: 50kDa
• NCBI Gene Id: 8797
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: Tumor necrosis factor receptor superfamily, member 10a
• Alias Symbols: DR4, APO2, CD261, TRAILR1, TRAILR-1
• Peptide Sequence: Synthetic peptide located within the following region: RAGTAGPGDALYAMLMKWVNKTGRNASIHTLLDALERMEERHAKEKIQDL
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Description of Target: This is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adaptor molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
• Protein Interactions: UBC; MARCH8; MARCH1; CFLAR; FADD; CUL3; TRAF2; CASP8; SQSTM1; TNFRSF10B; CBL; MOAP1; RASSF1; TNFRSF10D; TNFRSF10A; TNFSF10; MADD; BCL10; TRADD; RIPK1; DAP3; BTK; CD4; COL2A1; CASP10;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-TNFRSF10A (ARP30622_P050) antibody is Catalog # AAP30622
• Uniprot ID: O00220
• Protein Name: Tumor necrosis factor receptor superfamily member 10A
• Protein Accession #: NP_003835
• Purification: Affinity Purified
• Nucleotide Accession #: NM_003844
• Tested Species Reactivity: Human
• Gene Symbol: TNFRSF10A
• Predicted Species Reactivity: Human, Mouse
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Human: 100%; Mouse: 80%
• Image 1: Human ACHN
  
  WB Suggested Anti-TNFRSF10A Antibody
  Titration: 1.0 ug/ml
  Positive Control: ACHN Whole Cell