TNFRSF10A Peptide (AAP30622)

Data Sheet
 
Sku AAP30622
Old sku AAPP01275
Price $99.00
Name TNFRSF10A Peptide (AAP30622)
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Size 100 ug
Gene TNFRSF10A
Alias symbols APO2, CD261, DR4, MGC9365, TRAILR-1, TRAILR1
Gene id 8797
Description of target This is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adaptor molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
Swissprot id O00220
Protein accession num NP_003835
Nucleotide accession num NM_003844
Protein size 468 amino acids
Molecular weight 50kDa
Application WB
Partner proteins MOAP1,RASSF1,BCL10,BTK,CASP8,CD4,COL2A1,DAP3,FADD,MADD,MOAP1,RASSF1,RIPK1,TNFRSF10A,TNFRSF10B,TNFRSF10D,TNFSF10,TRADD,BCL10,CASP10,CASP8,CFLAR,DAP3,FADD,TNFSF10,TRADD
Quality control The peptide is characterized by mass spectroscopy
Key reference Pan, G. et al (1997) Science 276:111-113.
Description This is a synthetic peptide designed for use in combination with anti-TNFRSF10A antibody (Catalog #: AVARP02065_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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