| Product Number |
P100995_P050 |
| Product Page |
www.avivasysbio.com/cdk7-antibody-middle-region-p100995-p050.html |
| Name |
CDK7 Antibody - middle region (P100995_P050) |
| Protein Size (# AA) |
346 amino acids |
| Molecular Weight |
39kDa |
| NCBI Gene Id |
1022 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Cyclin-dependent kinase 7 |
| Description |
|
| Alias Symbols |
CAK, CAK1, HCAK, MO15, STK1, CDKN7, p39MO15 |
| Peptide Sequence |
Synthetic peptide located within the following region: TQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Li,Y., (2007) Lung Cancer 58 (2), 171-183 |
| Description of Target |
CDK7 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Protein Interactions |
UBC; RPA3; RPA2; RPA1; GTF2H4; GTF2H3; GTF2H2; GTF2H1; ERCC5; ERCC3; ERCC2; CDK7; CCNH; ATP2B4; A2M; GTF2H5; SRPK2; SRPK1; MNAT1; TP53; CDK2; CTD; MBP; CDK1; CCNB1; CCNA2; Dlg4; UVSSA; HSP90AA1; HSD17B4; HLA-DQA1; SUPT5H; POLR2A; GTF2E2; GTF2E1; CDK9; APP |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-CDK7 (P100995_P050) antibody |
| Blocking Peptide |
For anti-CDK7 (P100995_P050) antibody is Catalog # AAP31342 (Previous Catalog # AAPP02093) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human CDK7 |
| Uniprot ID |
P50613 |
| Protein Name |
Cyclin-dependent kinase 7 |
| Protein Accession # |
NP_001790 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_001799 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
CDK7 |
| Predicted Species Reactivity |
Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 80%; Dog: 86%; Guinea Pig: 78%; Horse: 86%; Human: 100%; Pig: 86%; Rat: 86% |
| Image 1 | Human THP-1
 | WB Suggested Anti-CDK7 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: THP-1 cell lysate |
|
