GRK1 Antibody (Phospho-Ser21) (OASG03219)

Data Sheet
 
Product Number OASG03219
Product Page www.avivasysbio.com/grk1-antibody-phospho-ser21-oasg03219.html
Name GRK1 Antibody (Phospho-Ser21) (OASG03219)
Molecular Weight 63 kDa
Isotype IgG
NCBI Gene Id 6011; 81760
Host Rabbit
Clonality Polyclonal
Concentration 1 mg/ml
Gene Full Name G protein-coupled receptor kinase 1
Alias Symbols RK, RHOK, GPRK1
Product Format Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Description of Target This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2).
Reconstitution and Storage Store at -20C. Avoid repeated freeze/thaw cycles.
Datasheets/Manuals Printable datasheet for anti-GRK1 (OASG03219) antibody
Specificity Phospho-GRK 1 (S21) Polyclonal Antibody detects endogenous levels of GRK 1 protein only when phosphorylated at S21.
Application Info WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;
Immunogen Synthesized peptide derived from human GRK 1 around the phosphorylation site of S21. Location: 1-80aa.
Uniprot ID Q15835, Q9WVL4, Q63651
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Target Post-Translational Modification Phospho-Ser21
Gene Symbol GRK1
Predicted Species Reactivity Human, Mouse, Rat, Monkey
Application WB, IHC
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