| Product Number |
OASG01837 |
| Product Page |
www.avivasysbio.com/crhr1-antibody-middle-region-oasg01837.html |
| Name |
CRHR1 Antibody - middle region (OASG01837) |
| Molecular Weight |
52 kDa |
| Isotype |
IgG |
| NCBI Gene Id |
1394; 12921; 58959 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1 mg/ml |
| Gene Full Name |
corticotropin releasing hormone receptor 1 |
| Description |
|
| Alias Symbols |
CRF1, CRHR, CRF-R, CRFR1, CRF-R1, CRFR-1, CRH-R1, CRHR1L, CRF-R-1, CRH-R-1 |
| Product Format |
Liquid. PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Description of Target |
This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Readthrough transcription also exists between this gene and upstream GeneID:401884 (ADP-ribosylation factor 3 pseudogene), and the readthrough transcripts encode isoforms that share similarity with the products of this gene. |
| Reconstitution and Storage |
Store at -20°C. Avoid repeated freeze/thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-CRHR1 (OASG01837) antibody |
| Specificity |
CRF-RI Polyclonal Antibody detects endogenous levels of CRF-RI protein. |
| Application Info |
WB1:500~2000
IHC1:100~300
IF1:200~1000
ELISA1:5000
|
| Immunogen |
Synthesized peptide derived from the Internal region of human CRF-RI. Location: 50-130aa. |
| Uniprot ID |
P34998, P35347, P35353 |
| Publications |
Orexin A Enhances Pro-Opiomelanocortin Transcription Regulated by BMP-4 in Mouse Corticotrope AtT20 Cells. Int J Mol Sci. 22 (2021) 33925368
Somatostatin receptor subtype 5 modifies hypothalamic-pituitary-adrenal axis stress function. JCI Insight. 3, (2018). 30282821 |
| Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Gene Symbol |
CRHR1 |
| Predicted Species Reactivity |
Human, Mouse, Rat |
| Application |
WB, IHC, IF, ELISA |
| Image 1 | HT29
 | Western Blot using HT29 |
|
|
