| Product Number |
OASA03787 |
| Product Page |
www.avivasysbio.com/gapdh-antibody-oasa03787.html |
| Name |
GAPDH Antibody (OASA03787) |
| Protein Size (# AA) |
333 amino acids |
| Clone |
6C5 |
| Isotype |
IgG1 |
| NCBI Gene Id |
100009074 |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Concentration |
1 mg/ml |
| Description |
|
| Product Format |
Liquid. Phosphate buffered saline |
| Description of Target |
MOUSE ANTI RABBIT GAPDH
|
| Reconstitution and Storage |
-20°C |
| Datasheets/Manuals |
Printable datasheet for GAPDH Antibody (OASA03787) |
| Specificity |
Mouse anti Rabbit GAPDH antibody, clone 6C5 recognizes glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a 36kD multifunctional protein whose main function is to catalyse the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, in conjunction with inorganic phosphate and nicotinamide adenine dinucleotide (NAD). This reaction is an important energy yielding step in carbohydrate metabolism.
GAPDH has also been shown to translocate to the nucleus under a variety of stressors, most of which are associated with oxidative stress, whereby it mediates cell death. A further report has shown that GAPDH binds to several proteins that are responsible for neurodegenerative diseases, such as amyloid precursor protein and Huntingtin (Hara et al. 2006).
|
| Additional Information |
Fusion Partners: Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line. |
| Additional Information |
Preservative Stabilisers: 0.09% Sodium Azide (NaN3) |
| Immunogen |
Rabbit muscle GAPDH. |
| Additional Information |
Approx Protein Conc: IgG concentration 1.0mg/ml
Buffer Solutions: Phosphate buffered saline |
| Uniprot ID |
P46406 |
| Protein Name |
Glyceraldehyde-3-phosphate dehydrogenase |
| Publications |
The analysis of heterotaxy patients reveals new loss-of-function variants of GRK5. Sci Rep. 6, 33231 (2016). 27618959 |
| Protein Accession # |
NP_001075722.1 |
| Purification |
Protein A Purified |
| Gene Symbol |
GAPDH |
| Predicted Species Reactivity |
Rabbit |
| Application |
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Frozen|Immunoprecipitation|Western blot |
| Predicted Homology Based on Immunogen Sequence |
Rabbit |
| Image 1 | |
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