| Product Number |
OAMA00660 |
| Product Page |
www.avivasysbio.com/papp-a-antibody-oama00660.html |
| Name |
PAPP-A Antibody (OAMA00660) |
| Clone |
11E4 |
| Isotype |
IgG2b |
| NCBI Gene Id |
5069 |
| Host |
Mouse. Hybridization of SP2/0 myeloma cells with spleen cells from Balb/c mice. Source: Ascites |
| Clonality |
Monoclonal |
| Purity |
>90% pure (SDS-PAGE). Protein A chromatography. |
| Gene Full Name |
pregnancy-associated plasma protein A |
| Alias Symbols |
PAPA, DIPLA1, PAPP-A, PAPPA1, ASBABP2, IGFBP-4ase |
| Product Format |
Purified, Liquid |
| Description of Target |
Monoclonal Antibody to Human Pregnancy Associated Plasma Protein A (PAPP-A), proMBP subunit |
| Reconstitution and Storage |
Store at 2 to 8C. |
| Datasheets/Manuals |
Printable datasheet for OAMA00660 |
| Specificity |
Specific to the proMBP subunit of heterotetrameric PAPP-A (htPAPP-A; PAPP-A/proMBP). Human PAPP-A antigen purified from placental blood is a heterotetrameric complex, consisting of two PAPP-A subunits and two pro-MBP subunits). Human PAPP-A antigen purified from atherosclerotic plaques is homodimeric consisting of 2 PAPP-A subunits. |
| Additional Information |
Affinity Constant: Not determined |
| Application Info |
Detection of human htPAPP-A antigen in immunoassay and immunoprecipitation. Recognizes proMBP subunit in Western blot. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Recommended pair for detection of htPAPP-A in sandwich immunoassay:
Capture Antibody |
Detection Antibody |
OAMA00654 |
OAMA00660 |
|
| Immunogen |
Purified human PAPP-A/proMBP heterotetrameric complex (htPAPP-A) |
| Additional Information |
Buffer: PBS, pH 7.4
Preservative: 0.1% Sodium Azide
Important Note: Centrifuge before opening to ensure complete recovery of vial contents.
Warnings: This product contains sodium azide, which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains. |
| Uniprot ID |
Q13219 |
| Protein Name |
Pappalysin-1 |
| Protein Accession # |
NP_002572.2 |
| Purification |
Purified |
| Gene Symbol |
PAPPA |
| Application |
Enzyme immunoassay, Western blot |
| Image 1 | |
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