C5AR2 Antibody (OAGA00046)

• Product Number: OAGA00046
• Name: C5AR2 Antibody (OAGA00046)
• Molecular Weight: 36 kDa
• Isotype: IgG
• NCBI Gene Id: 27202
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 1 mg/ml
• Gene Full Name: C5a anaphylatoxin chemotactic receptor 2
• Alias Symbols: C5L2, GPF77, GPR77
• Product Format: Liquid
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Additional Information: Background: The anaphylatoxins C3a (see MIM 120700), C4a (see MIM 120810), and C5a are cationic fragments generated during the complement cascade that participate in host defense. In the case of inappropriate complement activation, anaphylatoxins may be involved in autoimmunity and sepsis. C5L2 is coexpressed with the C5a receptor, C5AR (C5R1; MIM 113995), on polymorphonuclear neutrophils and may modulate C5AR activity (Gerard et al., 2005 [PubMed 16204243]).[supplied by OMIM]
• Additional Information: Positive Controls: 293T, A431, H1299, HeLa, Molt-4, Raji
• Application Info: Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Immunogen: Synthetic peptide corresponding to a region within amino acids 248 and 337 of GPR77 (Uniprot ID#Q9P296)
• Additional Information: Cellular Localization: Cell membrane
• Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Uniprot ID: Q9P296
• Protein Name: C5a anaphylatoxin chemotactic receptor C5L2
• Protein Accession #: NP_060955.1
• Purification: Purified by antigen-affinity chromatography.
• Gene Symbol: C5AR2
• Predicted Species Reactivity: Human
• Application: WB
• Image 1: HeLa, Molt-4
  
  Sample (30 ug of whole cell lysate)
  A: HeLa
  B: Molt-4
  10% SDS PAGE
  OAGA00046 diluted at 1:1000