| Product Number |
OACA08541 |
| Product Page |
www.avivasysbio.com/baat-antibody-oaca08541.html |
| Name |
BAAT Antibody (OACA08541) |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| NCBI Gene Id |
570 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Gene Full Name |
bile acid-CoA:amino acid N-acyltransferase |
| Alias Symbols |
BACAT;BACD1;BAT;bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase);bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase);bile acid-CoA thioesterase;bile acid-CoA:amino acid N-acyltransferase;choloyl-CoA hydrolase;Glycine N-choloyltransferase;HCHO;long-chain fatty-acyl-CoA hydrolase. |
| Product Format |
Liquid |
| Description of Target |
Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs. |
| Reconstitution and Storage |
-20°C or -80°C |
| Datasheets/Manuals |
Printable datasheet for BAAT Antibody (OACA08541) (OACA08541) |
| Immunogen |
Recombinant Human Bile acid-CoA:amino acid N-acyltransferase protein (309-418AA) |
| Formulation |
PBS with, 50% glycerol, pH7.3. |
| Uniprot ID |
Q14032 |
| Protein Name |
Bile acid-CoA:amino acid N-acyltransferase |
| Protein Accession # |
NP_001121082 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_001127610 |
| Preservative |
0.02% sodium azide |
| Gene Symbol |
BAAT |
| Predicted Species Reactivity |
Human|Mouse |
| Application |
Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot |
| Image 1 | Mouse liver tissue
 | Western blot
All lanes: BAAT antibody IgG at 3.73ug/ml+ Mouse liver tissue
Secondary
Goat polyclonal to rabbit IgG at 1/1,0000 dilution
Predicted band size: 46 kDa
Observed band size: 46 kDa
|
| | Image 2 | Human liver cancer
 | Immunohistochemistry of paraffin-embedded human liver cancer at dilution 1:100 |
| | Image 3 | Human lung cancer
 | Immunohistochemistry of paraffin-embedded human lung cancer at dilution 1:100 |
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