| Product Number |
OACA07666 |
| Product Page |
www.avivasysbio.com/sost-antibody-oaca07666.html |
| Name |
SOST Antibody (OACA07666) |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| NCBI Gene Id |
50964 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Gene Full Name |
sclerostin |
| Alias Symbols |
CDD;DAND6;sclerostin;SOST1;VBCH. |
| Product Format |
Liquid |
| Reference |
[1]"Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein."Brunkow M.E., Gardner J.C., Van Ness J., Paeper B.W., Kovacevich B.R., Proll S., Skonier J.E., Zhao L., Sabo P.J., Fu Y.H., Alisch R.S., Gillett L., Colbert T., Tacconi P., Galas D., Hamersma H., Beighton P., Mulligan J.T. Am. J. Hum. Genet. 68:577-589(2001). [2]"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L. Nusbaum C. Nature 440:1045-1049(2006). [3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."The MGC Project TeamGenome Res. 14:2121-2127(2004). |
| Description of Target |
Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. |
| Reconstitution and Storage |
-20°C or -80°C |
| Datasheets/Manuals |
Printable datasheet for SOST Antibody (OACA07666) (OACA07666) |
| Immunogen |
Recombinant Human Sclerostin protein (24-213AA) |
| Formulation |
PBS with, 50% glycerol, pH7.3. |
| Uniprot ID |
Q9BQB4 |
| Protein Name |
Sclerostin |
| Protein Accession # |
NP_079513 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_025237 |
| Preservative |
0.02% sodium azide |
| Gene Symbol |
SOST |
| Predicted Species Reactivity |
Human |
| Application |
Enzyme-linked immunosorbent assay|Immunohistochemistry |
| Image 1 | Human breast cancer
 | Immunohistochemistry of paraffin-embedded human breast cancer at dilution 1:100 |
| | Image 2 | Human kidney
 | Immunohistochemistry of paraffin-embedded human kidney at dilution 1:100 |
| | Image 3 | Human liver
 | Immunohistochemistry of paraffin-embedded human liver at dilution 1:100 |
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