| Product Number |
OAAJ02299 |
| Product Page |
www.avivasysbio.com/ikbkb-antibody-phospho-tyr188-oaaj02299.html |
| Name |
IKBKB Antibody (Phospho-Tyr188) (OAAJ02299) |
| Molecular Weight |
87 kDa |
| NCBI Gene Id |
3551 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1 mg/ml |
| Gene Full Name |
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| Alias Symbols |
IKK2, IKKB, IMD15, IMD15A, IMD15B, NFKBIKB, IKK-beta |
| Product Format |
Liquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Description of Target |
IKK-beta is a kinase of the IKK family. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Preferentially found as a heterodimer with IKK-alpha but also as an homodimer. |
| Reconstitution and Storage |
Store at -20C. Stable for 12 months from date of receipt. |
| Datasheets/Manuals |
Printable datasheet for anti-IKBKB (OAAJ02299) antibody |
| Specificity |
Phospho-IKK- beta (Tyr188) antibody detects endogenous levels of IKK- beta only when phosphorylated at Tyrosine 188 |
| Application Info |
WB: 1:500-1:2000 IHC: 1:50-1:200 |
| Immunogen |
A synthesized peptide derived from human IKK- beta around the phosphorylation site of Tyrosine 188 |
| Uniprot ID |
O14920 |
| Purification |
Immunogen affinity purified |
| Gene Symbol |
IKBKB |
| Predicted Species Reactivity |
Human, Mouse, Rat |
| Application |
WB, IHC |
| Image 1 | COS7 whole cell lysates
 | Western blot analysis of IKK- beta phosphorylation expression in COS7 whole cell lysates. The lane on the left is treated with the antigen-specific peptide. |
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